Wouldn't necessarily need forged internals, but a standalone ecu is a must.
Tbh the RON rating is pretty much useless, its the MON rating that is more important, yet this isn't published. Plus you need to know the British thermal unit (energy of fuel) to get the most of the setup. Normal pump fuel is like 13,000 BTU, yet Methanol is somewhere around 4000 BTU, hence you have to burn Meth at rich mixtures like 5:1 AFR.